Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | F9 | P00740 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | F11 | P03951 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 2/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10140042 | 0.89 | ATR (0.44) | CA12CA9F9F10F11 | |
| SCHEMBL7970080 | 0.85 | CA12 (0.35) | CA12CA9F9F10F11 | |
| SCHEMBL7970443 | 0.84 | ATR (0.39) | CA12CA9F9F10F11 | |
| SCHEMBL10140043 | 0.81 | TMEM97 (0.42) | MMP2MMP9MMP8MMP13PTGDR2 | |
| SCHEMBL7973945 | 0.81 | MEN1 (0.38) | ATRCHEK2KDM4EMEN1ALDH1A1 | |
| SCHEMBL7970581 | 0.80 | F9 (0.40) | CA12CA9F9F10F11 | |
| SCHEMBL7973155 | 0.80 | F9 (0.39) | CA12CA9F9F10F11 | |
| SCHEMBL7972135 | 0.79 | PDE10A (0.37) | CA12CA9F9F10F11 | |
| SCHEMBL7971018 | 0.78 | HSD17B10 (0.37) | CA12CA9F9F10F11 | |
| SCHEMBL10139808 | 0.76 | P2RY6 (0.53) | CA12CA9F9F10F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |