Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 16/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 15/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 14/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 14/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2974540 | 1.00 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL2971585 | 0.95 | PDE4B (0.47) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL5704569 | 0.95 | PDE4B (0.47) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL5704606 | 0.91 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL2981308 | 0.91 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL2976024 | 0.81 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2976708 | 0.81 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2978219 | 0.81 | PDE4B (0.42) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL2976079 | 0.80 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2980306 | 0.76 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235736-B1 | ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0994100-A1 | 3-ANILINO-2-CYCLOALKENONE DERIVATES | Nikken Chemicals Company, Limited (JP) | 2000-04-19 | — | — | EP | disclosed |