SCHEMBL7973474

SCHEMBL7973474

COc1c(N)c(F)c(F)c(OC)c1F

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10524905 0.92 HSD17B10 (0.38) HSD17B10
SCHEMBL6832953 0.89 HSD17B10 (0.44) HSD17B10
SCHEMBL16059218 0.83 HSD17B10 (0.39) HSD17B10
SCHEMBL3763099 0.80 HSD17B10 (0.41) HSD17B10
SCHEMBL25038845 0.78 HSD17B10 (0.31) HSD17B10
SCHEMBL6757630 0.78 HSD17B10 (0.38) HSD17B10
SCHEMBL31299646 0.78 MAPT (0.33) HSD17B10
SCHEMBL8072958 0.78 HSD17B10 (0.34) HSD17B10
SCHEMBL2493661 0.78 HSD17B10 (0.39) HSD17B10
Hydrochloric Acid SCHEMBL6756049 0.77 HSD17B10 (0.37) HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6229055-B1 SYNTHESIS OF FLUORINATED RESORCINOL WHICH IS USEFUL IN THE PREPARATION OF FLUORINATED FLUORESCEIN AND RHODOL DYES SUITABLE FOR USE AS TRACERS, LABELS, OR INTERMEDIATES MOLECULAR PROBES, INC. 2001-05-08 US disclosed
US-6162931-A Fluorinated xanthene derivatives MOLECULAR PROBES, INC. (US) 2000-12-19 US disclosed