Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | QRFPR | Q96P65 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PNLIP | P16233 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7562887 | 0.99 | ATM (0.43) | ATMKMT2AQRFPRMEN1MAPT | |
| SCHEMBL7563123 | 0.90 | ATM (0.44) | ATMKMT2AQRFPRMEN1MAPT | |
| SCHEMBL7566508 | 0.87 | SLC6A4 (0.50) | ATMKMT2AQRFPRMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7562396 | 0.86 | SLC6A4 (0.49) | ATMKMT2AQRFPRMEN1MAPT | |
| SCHEMBL7564238 | 0.84 | ATM (0.40) | ATMKMT2AQRFPRMEN1MAPT | |
| SCHEMBL7565818 | 0.84 | ATM (0.40) | ATMKMT2AQRFPRMEN1MAPT | |
| Hydrochloric Acid SCHEMBL7563160 | 0.84 | KMT2A (0.51) | KMT2AQRFPRMEN1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL7570727 | 0.83 | ATM (0.39) | ATMKMT2AQRFPRMEN1MAPT | |
| Hydrochloric Acid SCHEMBL7566307 | 0.83 | ATM (0.39) | ATMKMT2AQRFPRMEN1MAPT | |
| SCHEMBL7562365 | 0.83 | ATM (0.39) | ATMKMT2AQRFPRMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001046171-A1 | AMIDINE DERIVATIVES WHICH ARE INHIBITORS OF NITRIC OXIDE SYNTHASE | ASTRAZENECA AB (SE) | 2001-06-28 | — | — | WO | disclosed |