Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PLEC | Q15149 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960468 | 0.83 | PTGER4 (0.50) | PTGER4GAAKDM4EMAPTALDH1A1 | |
| SCHEMBL7973995 | 0.81 | PRSS1 (0.50) | PTGER4GAAKDM4EMAPTALDH1A1 | |
| SCHEMBL12283819 | 0.81 | PTGER4 (0.73) | PTGER4GAAKDM4EMAPTALDH1A1 | |
| SCHEMBL13462200 | 0.76 | PRKCI (0.67) | PTGER4GAAKDM4EMAPTALDH1A1 | |
| SCHEMBL5881658 | 0.72 | HPGD (0.49) | PTGER4GAAKDM4EMAPTALDH1A1 | |
| SCHEMBL6865515 | 0.70 | MAPT (0.48) | GAAKDM4EMAPTALDH1A1THRB | |
| SCHEMBL15173317 | 0.70 | HSP90AA1 (0.45) | GAAKDM4EMAPTALDH1A1GFER | |
| SCHEMBL22908891 | 0.70 | PRSS1 (0.69) | PTGER4GAAKDM4EMAPTALDH1A1 | |
| SCHEMBL7960466 | 0.69 | PTGER4 (0.52) | PTGER4GAAKDM4EMAPTALDH1A1 | |
| SCHEMBL5591978 | 0.68 | HPGD (0.48) | PTGER4GAAKDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204264-B1 | Benzimidazole derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO., LTD. (JP) | 2001-03-20 | — | — | US | disclosed |