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Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7974075

COC(=O)C1(Cc2cccc(OC(F)(F)F)c2)CCN(Cc2cncn2Cc2ccc(C#N)cc2)CC1.O=C(O)C(F)(F)F

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ FNTA P49354 16/20 0.64
▸ FNTB P49356 16/20 0.64
▸ PGGT1B P53609 14/20 0.64
▸ CYP11B1 P15538 3/20 0.44
▸ CYP11B2 P19099 3/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7842402 0.97 FNTA (0.67) FNTAFNTBPGGT1BCYP11B1CYP11B2
Trifluoroacetic Acid SCHEMBL7843101 0.90 FNTA (0.51) FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL7839747 0.88 FNTA (0.59) FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL7829982 0.88 FNTA (0.57) FNTAFNTBPGGT1BCYP11B1CYP11B2
Trifluoroacetic Acid SCHEMBL7837600 0.87 FNTA (0.52) FNTAFNTBPGGT1BL3MBTL1
Hydrochloric Acid SCHEMBL7843367 0.87 FNTA (0.57) FNTAFNTBPGGT1BCYP11B1CYP11B2
Trifluoroacetic Acid SCHEMBL7845788 0.87 FNTA (0.63) FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL7838094 0.85 FNTA (0.66) FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL7831054 0.85 FNTA (0.54) FNTAFNTBPGGT1BCYP11B1CYP11B2
SCHEMBL7831376 0.84 FNTA (0.54) FNTAFNTBPGGT1BL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6248756-B1 Inhibitors of farnesyl-protein transferase MERCK & CO., INC. 2001-06-19 — — US disclosed