Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 1.00 |
| ▸ | LMNA | P02545 | 5/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | HPGD | P15428 | 5/20 | 0.73 |
| ▸ | GAA | P10253 | 1/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | RORC | P51449 | 4/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.67 |
| ▸ | NPY2R | P49146 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725134 | 0.87 | MAPT (0.77) | MAPTLMNANPSR1ALDH1A1HPGD | |
| SCHEMBL4728744 | 0.85 | MAPT (0.74) | MAPTLMNANPSR1ALDH1A1HPGD | |
| SCHEMBL7722815 | 0.85 | NPSR1 (1.00) | MAPTLMNANPSR1ALDH1A1HPGD | |
| SCHEMBL4727375 | 0.85 | MAPT (0.73) | MAPTLMNANPSR1ALDH1A1HPGD | |
| SCHEMBL7977193 | 0.84 | NPSR1 (0.78) | MAPTLMNANPSR1ALDH1A1HPGD | |
| SCHEMBL14199692 | 0.84 | MAPT (0.82) | MAPTLMNANPSR1ALDH1A1HPGD | |
| SCHEMBL7977191 | 0.84 | NPSR1 (0.78) | MAPTLMNANPSR1ALDH1A1HPGD | |
| SCHEMBL7929907 | 0.82 | MAPT (0.79) | MAPTLMNANPSR1ALDH1A1HPGD | |
| SCHEMBL1593423 | 0.82 | MAPT (0.79) | MAPTLMNANPSR1ALDH1A1HPGD | |
| SCHEMBL4863449 | 0.82 | MAPT (0.79) | MAPTLMNANPSR1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |