Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.75 |
| ▸ | F10 | P00742 | 8/20 | 0.75 |
| ▸ | FURIN | P09958 | 1/20 | 0.75 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.69 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.69 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6579180 | 0.86 | F2 (1.00) | F2F10FURINPRSS1PRSS2 | |
| SCHEMBL6576993 | 0.83 | F10 (1.00) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL28928530 | 0.82 | F10 (0.61) | F2F10FURINPRSS1PRSS2 | |
| SCHEMBL23235805 | 0.82 | PRSS1 (0.67) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL428920 | 0.82 | PRSS1 (1.00) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL12348321 | 0.80 | PRSS1 (0.77) | F2PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL23541004 | 0.80 | PRSS1 (0.96) | F2F10PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL427173 | 0.80 | PRSS1 (0.96) | F2F10PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL28548914 | 0.80 | PRSS1 (0.96) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL6580964 | 0.79 | F10 (0.80) | F2F10PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306884-B1 | ANTICOAGULANTS AND BLOOD COAGULATION FACTOR | BERLEX LABORATORIES, INC. | 2001-10-23 | — | — | US | disclosed |
| US-6034103-A | THROMBOSIS THERAPY | BERLEX LABORATORIES, INC. (US) | 2000-03-07 | — | — | US | disclosed |
| US-5889005-A | Benzamidine derivatives and their use for treating thrombotic diseases | BERLEX LABORATORIES, INC. (US) | 1999-03-30 | — | — | US | disclosed |