⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691076 | 1.00 | — | — | |
| SCHEMBL9380636 | 0.78 | — | — | |
| SCHEMBL1499956 | 0.78 | — | — | |
| SCHEMBL9113778 | 0.78 | — | — | |
| SCHEMBL9879310 | 0.78 | — | — | |
| SCHEMBL7292878 | 0.78 | — | — | |
| SCHEMBL9113768 | 0.78 | — | — | |
| SCHEMBL8108021 | 0.78 | — | — | |
| SCHEMBL22182586 | 0.78 | — | — | |
| SCHEMBL1499957 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115843247-A | Compounds and methods for treating neurodegenerative diseases | 麦克莱恩医院公司 | 2023-03-24 | — | — | CN | disclosed |
| US-6274620-B1 | 2-BENZENESULFONYLAMINO-3-((5-BROMO-THIOPHENE-2-CARBONYL)-AMINO )PROPIONIC ACID-TERT-BUTYL ESTERS AS ANGIOGENESIS INHIBITORS; ANTICARCINOGENIC AGENTS; OSTEOPOROSIS, RESTENOSIS, AND OCULAR NEOVASCULARIZATION | BIOCHEM PHARMA INC. (CA) | 2001-08-14 | — | — | US | disclosed |
| US-6166003-A | Heterocyclic compounds for cancer chemoprevention | LKT LABORATORIES, INC. (US) | 2000-12-26 | — | — | US | disclosed |
| WO-2000049013-A1 | ISOTHIO CYANATO ALKYLTHIOPHENES AS CANCER CHEMOPROTECTIVE AGENTS | LKT LABORATORIES, INC. (US) | 2000-08-24 | — | — | WO | disclosed |
| EP-0557305-A1 | (2-THIENYL) ALKYLAMINE DERIVATIVES HAVING NEUROPROTECTIVE PROPERTIES. | FISONS CORP (US) | 1993-09-01 | — | — | EP | disclosed |
| US-5109017-A | (2-thienyl)alkylamine derivatives having neuroprotective properties | FISONS CORPORATION (US) | 1992-04-28 | — | — | US | disclosed |
| US-5109017-A | (2-thienyl)alkylamine derivatives having neuroprotective properties | FISONS CORPORATION (US) | 1992-04-28 | — | — | US | disclosed |
| WO-1992005169-A1 | (2-THIENYL) ALKYLAMINE DERIVATIVES HAVING NEUROPROTECTIVE PROPERTIES | FISONS CORPORATION (US) | 1992-04-02 | — | — | WO | disclosed |
| EP-0274434-A1 | Dopamine-beta-hydroxylase inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 1988-07-13 | — | — | EP | disclosed |
| US-4749717-A | 1-(2- OR 3-THIENYLALKYL)IMIDAZOLE-2-THIOLS AND 1-(2- OR 3-THIENYLALKYL)-2-ALKLYTHIOMIDAZOLES; HYPOTENSIVE AGENT, DIURETIC | SMITHKLINE BECKMAN CORPORATION (US) | 1988-06-07 | — | — | US | disclosed |