Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26568588 | 0.86 | DAO (0.44) | DAOHTTALDH1A1MAOAMAOB | |
| SCHEMBL8951118 | 0.84 | DAO (0.43) | DAOHTTALDH1A1MAOAMAOB | |
| SCHEMBL16105820 | 0.81 | DAO (0.55) | DAOHTTALDH1A1MAOAMAOB | |
| SCHEMBL895460 | 0.80 | CYP2D6 (0.49) | DAOHTTALDH1A1ALOX15MAOA | |
| SCHEMBL19121747 | 0.78 | SKP2 (0.50) | DAOHTTALDH1A1 | |
| SCHEMBL16953418 | 0.78 | DAO (0.42) | DAOHTTALDH1A1IGF1RALOX15 | |
| SCHEMBL80232 | 0.78 | DAO (0.42) | DAOHTTALDH1A1IGF1RALOX15 | |
| SCHEMBL7496943 | 0.78 | DAO (0.42) | DAOHTTALDH1A1IGF1RALOX15 | |
| SCHEMBL80635 | 0.78 | HTT (0.46) | DAOHTTALDH1A1IGF1RALOX15 | |
| SCHEMBL28209204 | 0.78 | DAO (0.46) | DAOHTTALDH1A1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37303-E1 | Imidazole compounds and their therapeutic applications | INSTITUT NATIONAL DEL LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2001-07-31 | — | — | US | disclosed |
| US-5708171-A | HISTAMINE H3-RECEPTOR ANTAGONIST | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1998-01-13 | — | — | US | disclosed |
| US-5559113-A | ANTAGONISTS TO HISTAMINE H3 RECEPTORS, SEDATIVES, ANTICONVULSANTS, ANTIULCER AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE | 1996-09-24 | — | — | US | disclosed |