Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 8/20 | 0.52 |
| ▸ | FNTB | P49356 | 8/20 | 0.52 |
| ▸ | PGGT1B | P53609 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GPR6 | P46095 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7848662 | 0.99 | FNTA (0.52) | FNTAFNTBPGGT1BLMNAGPR6 | |
| SCHEMBL7840263 | 0.92 | FNTA (0.53) | FNTAFNTBPGGT1BLMNAMEN1 | |
| SCHEMBL7840048 | 0.90 | FNTA (0.56) | FNTAFNTBPGGT1BMEN1KMT2A | |
| SCHEMBL7840536 | 0.88 | FNTA (0.54) | FNTAFNTBPGGT1BLMNAMEN1 | |
| Trifluoroacetic Acid SCHEMBL7850384 | 0.87 | FNTA (0.56) | FNTAFNTBPGGT1BGPR6MEN1 | |
| SCHEMBL7831376 | 0.86 | FNTA (0.54) | FNTAFNTBPGGT1BLMNAGPR6 | |
| SCHEMBL7839218 | 0.85 | FNTA (0.65) | FNTAFNTBPGGT1B | |
| SCHEMBL7852114 | 0.85 | FNTA (0.67) | FNTAFNTBPGGT1BLMNAGPR6 | |
| Hydrochloric Acid SCHEMBL7840645 | 0.85 | FNTA (0.66) | FNTAFNTBPGGT1BLMNAGPR6 | |
| Hydrochloric Acid SCHEMBL7843273 | 0.85 | FNTA (0.65) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248756-B1 | Inhibitors of farnesyl-protein transferase | MERCK & CO., INC. | 2001-06-19 | — | — | US | disclosed |