Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PEPD | P12955 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL624298 | 0.93 | ACE (0.42) | ACELMNAHSD17B10CYP2C19KDM4E | |
| SCHEMBL9105160 | 0.84 | HTT (0.41) | ACELMNAHSD17B10CYP2C19REN | |
| SCHEMBL1360593 | 0.84 | CYP1A2 (0.40) | ACELMNAHSD17B10CYP2C19KDM4E | |
| SCHEMBL1360596 | 0.84 | HTT (0.41) | ACELMNAHSD17B10CYP2C19REN | |
| SCHEMBL9090390 | 0.82 | ACE (0.41) | ACELMNAHSD17B10CYP2C19KDM4E | |
| SCHEMBL9090397 | 0.82 | ACE (0.41) | ACELMNAHSD17B10CYP2C19KDM4E | |
| SCHEMBL2638664 | 0.82 | NR1I2 (0.55) | ACELMNAHSD17B10CYP2C19KDM4E | |
| SCHEMBL8892725 | 0.82 | NR1I2 (0.55) | ACELMNAHSD17B10CYP2C19KDM4E | |
| SCHEMBL13974938 | 0.82 | NR1I2 (0.55) | ACELMNAHSD17B10CYP2C19KDM4E | |
| SCHEMBL608771 | 0.81 | ACE (0.39) | ACELMNAHSD17B10CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111004314-A | Preparation method of iron protein succinate with high iron loading capacity | 江苏中天药业有限公司 | 2020-04-14 | — | — | CN | disclosed |
| US-6204385-B1 | REACTING THE CORRESPONDING NITRILE WITH AMMONIA, AMINE OR HYDRAZINE IN THE PRESENCE OF A MERCAPTOCARBOXYLIC ACID | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-20 | — | — | US | disclosed |
| EP-0931069-B1 | PROCESS FOR PREPARING AMIDINES | BASF AG (DE) | 2000-11-29 | — | — | EP | disclosed |
| EP-0931069-A1 | PROCESS FOR PREPARING AMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 1999-07-28 | — | — | EP | disclosed |
| WO-1998009950-A1 | PROCESS FOR PREPARING AMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 1998-03-12 | — | — | WO | disclosed |