Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7974573

Cc1ccccc1CC1(CO)CCN(Cc2cncn2Cc2ccc(C#N)cc2)CC1.O=C(O)C(F)(F)F

nearest known ligand 0.60

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Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FNTA P49354 20/20 0.60
FNTB P49356 20/20 0.60
PGGT1B P53609 16/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7973979 0.93 FNTA (0.63) FNTAFNTBPGGT1B
SCHEMBL7974575 0.89 FNTA (0.65) FNTAFNTBPGGT1B
SCHEMBL7831554 0.86 POLB (0.60) FNTAFNTBPGGT1B
SCHEMBL7972324 0.84 FNTA (0.57) FNTAFNTBPGGT1B
Trifluoroacetic Acid SCHEMBL7842732 0.83 FNTA (0.52) FNTAFNTBPGGT1B
SCHEMBL7851850 0.83 FNTA (0.63) FNTAFNTBPGGT1B
SCHEMBL7839757 0.82 FNTA (0.65) FNTAFNTBPGGT1B
SCHEMBL7842611 0.81 FNTA (0.62) FNTAFNTBPGGT1B
SCHEMBL7853068 0.81 FNTA (0.65) FNTAFNTBPGGT1B
SCHEMBL7855834 0.81 FNTA (0.54) FNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6248756-B1 Inhibitors of farnesyl-protein transferase MERCK & CO., INC. 2001-06-19 US disclosed