Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22336451 | 0.80 | KMT2A (0.54) | MEN1KMT2AMAPTNPY5RBCHE | |
| SCHEMBL6986693 | 0.80 | MEN1 (0.56) | MEN1KMT2AMAPTNPY5RLMNA | |
| SCHEMBL1149958 | 0.78 | MEN1 (1.00) | MEN1KMT2AMAPTNPY5RLMNA | |
| SCHEMBL13049601 | 0.76 | KMT2A (0.50) | MEN1KMT2AMAPTNPY5RBCHE | |
| SCHEMBL6827501 | 0.76 | MEN1 (0.54) | MEN1KMT2AMAPTNPY5RLMNA | |
| SCHEMBL27604176 | 0.75 | KMT2A (0.57) | MEN1KMT2AMAPTNPY5RLMNA | |
| SCHEMBL7976761 | 0.73 | TDP1 (0.36) | MEN1KMT2AMAPTLMNAHSD17B10 | |
| SCHEMBL150044 | 0.73 | BCHE (0.59) | MEN1KMT2AMAPTNPY5RLMNA | |
| SCHEMBL29780042 | 0.73 | BCHE (0.59) | MEN1KMT2AMAPTNPY5RLMNA | |
| SCHEMBL12320800 | 0.71 | POLB (0.57) | MEN1KMT2AMAPTLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |