Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | YAP1 | P46937 | 3/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | REN | P00797 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986565 | 0.94 | ADORA1 (0.55) | ADORA1YAP1PTPN1HRH2HRH1 | |
| SCHEMBL7975494 | 0.93 | ADORA1 (0.56) | ADORA1HRH2HRH1KMT2AHCRTR2 | |
| SCHEMBL7992634 | 0.85 | HCRTR2 (0.43) | ADORA1YAP1PTPN1HRH2HRH1 | |
| SCHEMBL7989016 | 0.84 | ADORA1 (0.54) | ADORA1KMT2AHCRTR2P2RX7 | |
| SCHEMBL7975784 | 0.82 | ADORA1 (0.53) | ADORA1HRH2HRH1KMT2AHCRTR2 | |
| SCHEMBL7987192 | 0.82 | ADORA1 (0.53) | ADORA1HRH2HRH1KMT2AHCRTR2 | |
| SCHEMBL7986071 | 0.81 | ADORA1 (0.52) | ADORA1KMT2AHCRTR2P2RX7 | |
| SCHEMBL7992666 | 0.81 | ADORA1 (0.56) | ADORA1HRH2HRH1KMT2AHCRTR2 | |
| SCHEMBL7975386 | 0.80 | ADORA1 (0.53) | ADORA1HRH2HRH1KMT2AHCRTR2 | |
| SCHEMBL7975232 | 0.80 | ADORA1 (0.51) | ADORA1HRH2HRH1KMT2AP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |