Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8297312 | 0.85 | SMN1; SMN2 (0.63) | SMN1; SMN2MEN1KMT2ACISD2HPGD | |
| SCHEMBL18254450 | 0.85 | CYP17A1 (0.46) | SMN1; SMN2GAATDP1GFERMEN1 | |
| SCHEMBL6233789 | 0.85 | GAA (0.54) | SMN1; SMN2GAATDP1MEN1KMT2A | |
| SCHEMBL15600352 | 0.84 | RXFP1 (0.47) | GAAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL17149602 | 0.81 | GAA (0.40) | SMN1; SMN2GAATDP1GFERMEN1 | |
| SCHEMBL6852142 | 0.81 | GAA (0.61) | GAATDP1MEN1KMT2AHPGD | |
| SCHEMBL9850862 | 0.78 | GAA (0.65) | SMN1; SMN2GAATDP1GFERMEN1 | |
| SCHEMBL14518047 | 0.77 | GAA (0.50) | SMN1; SMN2GAATDP1MEN1KMT2A | |
| SCHEMBL15151474 | 0.76 | GAA (0.44) | SMN1; SMN2GAAMEN1KMT2ANPC1 | |
| SCHEMBL2770751 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2MEN1KMT2ACISD2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214826-B1 | NERVOUS SYSTEM DISORDERS | ZENECA LIMITED (GB) | 2001-04-10 | — | — | US | disclosed |