Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 18/20 | 0.53 |
| ▸ | BCL2 | P10415 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975831 | 1.00 | MCL1 (0.53) | MCL1BCL2ALDH1A1LMNAMAPT | |
| SCHEMBL6847018 | 1.00 | MCL1 (0.53) | MCL1BCL2ALDH1A1LMNAMAPT | |
| SCHEMBL6847022 | 1.00 | MCL1 (0.53) | MCL1BCL2ALDH1A1LMNAMAPT | |
| SCHEMBL4313540 | 1.00 | MCL1 (0.53) | MCL1BCL2ALDH1A1LMNAMAPT | |
| SCHEMBL4313544 | 1.00 | MCL1 (0.53) | MCL1BCL2ALDH1A1LMNAMAPT | |
| SCHEMBL8999703 | 0.89 | MCL1 (0.52) | MCL1BCL2ALDH1A1LMNAMAPT | |
| SCHEMBL8999696 | 0.89 | MCL1 (0.52) | MCL1BCL2ALDH1A1LMNAMAPT | |
| SCHEMBL28845988 | 0.88 | MCL1 (0.44) | MCL1BCL2ALDH1A1LMNAMAPT | |
| SCHEMBL28845990 | 0.88 | MCL1 (0.44) | MCL1BCL2ALDH1A1LMNAMAPT | |
| SCHEMBL28845991 | 0.88 | MCL1 (0.44) | MCL1BCL2ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288036-B1 | ANTIINFLAMMATORY, ANTIASTHMATIC, ANTIALLERGEN, AND ANALGESIC AGENTS; ARGININE-CONTAINING NONA- OR DECAPEPTIDES | SCIOS INC. | 2001-09-11 | — | — | US | disclosed |
| EP-0618809-B1 | BRADYKININ TYPE PEPTIDES | SCIOS NOVA INC (US) | 1998-08-19 | — | — | EP | disclosed |