Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1038675 | 0.81 | — | — | |
| SCHEMBL1242598 | 0.81 | TSHR (0.45) | TSHRALDH1A1LMNA | |
| SCHEMBL1017561 | 0.79 | — | — | |
| SCHEMBL21385918 | 0.77 | — | — | |
| SCHEMBL1454032 | 0.77 | TSHR (0.52) | TSHRALDH1A1TDP1LMNA | |
| SCHEMBL8923024 | 0.77 | TSHR (0.52) | TSHRALDH1A1TDP1LMNA | |
| SCHEMBL1453559 | 0.77 | TSHR (0.52) | TSHRALDH1A1TDP1LMNA | |
| SCHEMBL1453438 | 0.77 | TSHR (0.52) | TSHRALDH1A1TDP1LMNA | |
| SCHEMBL815324 | 0.77 | TSHR (0.52) | TSHRALDH1A1TDP1LMNA | |
| SCHEMBL18863421 | 0.77 | TSHR (0.52) | TSHRALDH1A1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |