Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 18/20 | 0.71 |
| ▸ | HRH1 | P35367 | 18/20 | 0.71 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7250885 | 1.00 | HRH2 (0.71) | HRH2HRH1HRH3RAB9ADRD2 | |
| SCHEMBL7244819 | 1.00 | HRH2 (0.71) | HRH2HRH1HRH3RAB9ADRD2 | |
| SCHEMBL7248246 | 0.87 | HRH2 (0.76) | HRH2HRH1HRH3 | |
| SCHEMBL7976390 | 0.85 | HRH1 (0.67) | HRH2HRH1HRH3 | |
| SCHEMBL7978302 | 0.84 | HRH2 (0.61) | HRH2HRH1HRH3RAB9A | |
| SCHEMBL7243588 | 0.84 | HRH2 (0.61) | HRH2HRH1HRH3RAB9A | |
| SCHEMBL7245178 | 0.84 | HRH2 (0.61) | HRH2HRH1HRH3RAB9A | |
| SCHEMBL7248482 | 0.83 | HRH2 (1.00) | HRH2HRH1HRH3 | |
| SCHEMBL7242852 | 0.83 | HRH1 (0.70) | HRH2HRH1HRH3 | |
| SCHEMBL7244264 | 0.83 | HRH2 (1.00) | HRH2HRH1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001066534-A2 | CYCLIC AND BICYCLIC DIAMINO HISTAMINE-3 RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2001-09-13 | — | — | WO | claimed |
| WO-2001066534-A2 | CYCLIC AND BICYCLIC DIAMINO HISTAMINE-3 RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2001-09-13 | — | — | WO | disclosed |