Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976498 | 0.92 | KMT2A (0.44) | SMN1; SMN2L3MBTL1KMT2AALDH1A1KDM4E | |
| SCHEMBL8092195 | 0.84 | SMN1; SMN2 (0.40) | SMN1; SMN2L3MBTL1KMT2AALDH1A1GAA | |
| SCHEMBL7978944 | 0.84 | KMT2A (0.40) | SMN1; SMN2L3MBTL1KMT2AALDH1A1KDM4E | |
| SCHEMBL161624 | 0.83 | TSHR (0.44) | SMN1; SMN2L3MBTL1KMT2AALDH1A1RAB9A | |
| SCHEMBL7972625 | 0.82 | KMT2A (0.42) | SMN1; SMN2KMT2AALDH1A1HSD17B10RAB9A | |
| SCHEMBL22615998 | 0.82 | TSHR (0.41) | SMN1; SMN2L3MBTL1KMT2AALDH1A1GAA | |
| SCHEMBL22621360 | 0.82 | TSHR (0.41) | SMN1; SMN2L3MBTL1KMT2AALDH1A1GAA | |
| SCHEMBL22615882 | 0.82 | TSHR (0.41) | SMN1; SMN2L3MBTL1KMT2AALDH1A1GAA | |
| SCHEMBL7976395 | 0.82 | KMT2A (0.44) | SMN1; SMN2L3MBTL1KMT2AALDH1A1KDM4E | |
| SCHEMBL7972624 | 0.81 | KMT2A (0.41) | SMN1; SMN2L3MBTL1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268511-B1 | USED FOR PRODUCING COPOLYMER WITH ACRYLIC ESTER COMONOMERS; COPOLYMERS ARE USED FOR FOLDABLE INTRAOCULAR LENSES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-07-31 | — | — | US | disclosed |
| EP-0987247-A1 | ITACONATE DERIVATIVES USED FOR A COMPONENT OF A POLYMER | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2000-03-22 | — | — | EP | disclosed |