Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 18/20 | 0.69 |
| ▸ | HRH1 | P35367 | 18/20 | 0.69 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.64 |
| ▸ | MAOB | P27338 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7244490 | 0.88 | HRH2 (0.66) | HRH2HRH1HRH3MAOB | |
| SCHEMBL7243987 | 0.84 | HRH3 (0.75) | HRH2HRH1HRH3MAOB | |
| SCHEMBL7252564 | 0.83 | HRH3 (0.76) | HRH2HRH1HRH3MAOB | |
| SCHEMBL7244767 | 0.82 | HRH3 (0.78) | HRH2HRH1HRH3MAOB | |
| SCHEMBL7245910 | 0.81 | HRH3 (0.80) | HRH2HRH1HRH3MAOB | |
| SCHEMBL7245805 | 0.80 | HRH2 (0.78) | HRH2HRH1HRH3MAOB | |
| SCHEMBL7244924 | 0.80 | HRH2 (0.63) | HRH2HRH1HRH3MAOB | |
| SCHEMBL492129 | 0.79 | HRH3 (1.00) | HRH2HRH1HRH3MAOB | |
| SCHEMBL7244430 | 0.79 | HRH2 (0.68) | HRH2HRH1HRH3MAOB | |
| SCHEMBL7243930 | 0.79 | HRH2 (0.69) | HRH2HRH1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001066534-A2 | CYCLIC AND BICYCLIC DIAMINO HISTAMINE-3 RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2001-09-13 | — | — | WO | disclosed |