Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976395 | 0.86 | KMT2A (0.44) | POLBKMT2ATSHRADRA1DADRA1A | |
| SCHEMBL7962678 | 0.86 | KMT2A (0.44) | POLBKMT2ATSHRHTTALDH1A1 | |
| SCHEMBL7976398 | 0.84 | KMT2A (0.42) | POLBKMT2ATSHRADRA1DADRA1A | |
| SCHEMBL7972624 | 0.83 | KMT2A (0.41) | POLBKMT2ATSHRADRA1DADRA1A | |
| SCHEMBL7972625 | 0.82 | KMT2A (0.42) | POLBKMT2ATSHRADRA1DADRA1A | |
| SCHEMBL8092195 | 0.81 | SMN1; SMN2 (0.40) | POLBKMT2ATSHRADRA1DADRA1A | |
| SCHEMBL7342563 | 0.81 | KMT2A (0.49) | POLBKMT2ATSHRADRA1DADRA1A | |
| SCHEMBL7976498 | 0.81 | KMT2A (0.44) | POLBKMT2ATSHRADRA1DADRA1A | |
| SCHEMBL7976401 | 0.80 | POLB (0.46) | POLBKMT2ATSHRADRA1DADRA1A | |
| SCHEMBL22621360 | 0.80 | TSHR (0.41) | POLBKMT2ATSHRADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268511-B1 | USED FOR PRODUCING COPOLYMER WITH ACRYLIC ESTER COMONOMERS; COPOLYMERS ARE USED FOR FOLDABLE INTRAOCULAR LENSES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-07-31 | — | — | US | disclosed |
| EP-0987247-A1 | ITACONATE DERIVATIVES USED FOR A COMPONENT OF A POLYMER | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2000-03-22 | — | — | EP | disclosed |