Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2786495 | 0.88 | PPARG (0.84) | PPARGPPARA | |
| SCHEMBL9389101 | 0.86 | PPARG (0.73) | PPARGPPARA | |
| SCHEMBL13891652 | 0.85 | PPARG (0.79) | PPARGPPARA | |
| SCHEMBL7920689 | 0.85 | PPARG (0.77) | PPARGPPARA | |
| SCHEMBL7922711 | 0.85 | PPARG (0.80) | PPARGPPARA | |
| SCHEMBL13777316 | 0.85 | PPARG (0.72) | PPARGPPARA | |
| SCHEMBL9086989 | 0.85 | PPARG (0.80) | PPARGPPARA | |
| SCHEMBL9086967 | 0.85 | PPARG (0.80) | PPARGPPARA | |
| SCHEMBL9086937 | 0.85 | PPARG (1.00) | PPARGPPARA | |
| SCHEMBL7922721 | 0.85 | PPARG (0.80) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294580-B1 | FOR THERAPY AND PROPHYLAXIS OF TYPE II OR NON-INSULIN DEPENDENT DIABETES MELLITUS, HYPERGLYCAEMIA, DYSLIPIDEMIA, TYPE II DIABETES, TYPE I DIABETES, HYPERTRIGLYCERIDEMIA, SYNDROME X, INSULIN RESISTANCE, HEART FAILURE | GLAXO WELLCOME INC. | 2001-09-25 | — | — | US | disclosed |