Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.68 |
| ▸ | MEN1 | O00255 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | S100A4 | P26447 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.45 |
| ▸ | F2R | P25116 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11735178 | 0.82 | MAPT (0.59) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL1128287 | 0.82 | MAPT (0.71) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL150552 | 0.81 | MAPT (1.00) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL22129107 | 0.81 | MAPT (0.59) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL29420630 | 0.81 | MAPT (0.59) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL7976792 | 0.79 | MAPT (0.68) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL12320800 | 0.79 | POLB (0.57) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL31548612 | 0.79 | MAPT (0.68) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL18109210 | 0.79 | MAPT (0.68) | MAPTMEN1KMT2ALMNAPOLB | |
| SCHEMBL12181484 | 0.79 | MAPT (0.56) | MAPTMEN1KMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |