Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.65 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MFN2 | O95140 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL968900 | 0.89 | — | — | |
| SCHEMBL3195592 | 0.79 | EPHX2 (1.00) | EPHX2MMP2MMP8EPHX1NPC1 | |
| SCHEMBL967136 | 0.79 | — | — | |
| SCHEMBL966686 | 0.79 | — | — | |
| SCHEMBL3195603 | 0.79 | EPHX2 (1.00) | EPHX2MMP2MMP8EPHX1NPC1 | |
| SCHEMBL481972 | 0.77 | EPHX2 (0.68) | EPHX2MMP2MMP8EPHX1NPC1 | |
| SCHEMBL530140 | 0.77 | EPHX1 (0.64) | EPHX2MMP2MMP8EPHX1NPC1 | |
| SCHEMBL1757033 | 0.77 | EPHX1 (0.64) | EPHX2MMP2MMP8EPHX1NPC1 | |
| SCHEMBL1756850 | 0.77 | EPHX1 (0.64) | EPHX2MMP2MMP8EPHX1NPC1 | |
| SCHEMBL1498319 | 0.77 | EPHX2 (0.68) | EPHX2MMP2MMP8EPHX1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |