Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.62 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | PDE2A | O00408 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | MPL | P40238 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42905 | 0.83 | IDO1 (0.62) | IDO1DAOPDE2ACES2MPL | |
| Hydrochloric Acid SCHEMBL30525006 | 0.82 | IDO1 (0.66) | IDO1DAOPDE2ASLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL4496729 | 0.80 | IDO1 (0.64) | IDO1DAOPDE2ASLC6A4SLC6A2 | |
| SCHEMBL857195 | 0.79 | IDO1 (0.58) | IDO1DAOPDE2ASLC6A4SLC6A2 | |
| SCHEMBL5325907 | 0.79 | IDO1 (0.58) | IDO1DAOPDE2ASLC6A4SLC6A2 | |
| SCHEMBL6789942 | 0.79 | IDO1 (0.58) | IDO1DAOPDE2ASLC6A4SLC6A2 | |
| SCHEMBL29738028 | 0.79 | IDO1 (0.58) | IDO1DAOPDE2ASLC6A4SLC6A2 | |
| SCHEMBL17864260 | 0.79 | IDO1 (0.58) | IDO1DAOPDE2ASLC6A4SLC6A2 | |
| SCHEMBL27634838 | 0.79 | IDO1 (0.58) | IDO1DAOPDE2ASLC6A4SLC6A2 | |
| SCHEMBL507107 | 0.79 | IDO1 (0.62) | IDO1DAOPDE2ASLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |