Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.75 |
| ▸ | MAPT | P10636 | 10/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.67 |
| ▸ | RORC | P51449 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976971 | 0.90 | MAPT (0.71) | NPSR1MAPTKDM4ERORCLMNA | |
| SCHEMBL4729996 | 0.89 | NPSR1 (0.69) | NPSR1MAPTKDM4ERORCLMNA | |
| SCHEMBL7722815 | 0.86 | NPSR1 (1.00) | NPSR1MAPTKDM4ERORCLMNA | |
| SCHEMBL13179872 | 0.86 | NPSR1 (0.65) | NPSR1MAPTKDM4ERORCLMNA | |
| SCHEMBL12602780 | 0.83 | NPSR1 (0.60) | NPSR1MAPTKDM4ERORCLMNA | |
| SCHEMBL13144117 | 0.82 | NPSR1 (0.66) | NPSR1MAPTKDM4ERORCLMNA | |
| SCHEMBL21950067 | 0.81 | NPSR1 (0.57) | NPSR1MAPTKDM4ERORCLMNA | |
| SCHEMBL4728828 | 0.81 | NPSR1 (0.70) | NPSR1MAPTKDM4ERORCLMNA | |
| SCHEMBL4727375 | 0.81 | MAPT (0.73) | NPSR1MAPTKDM4ERORCLMNA | |
| SCHEMBL4863449 | 0.80 | MAPT (0.79) | NPSR1MAPTKDM4ERORCLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |