Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.96 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.81 |
| ▸ | ATM | Q13315 | 4/20 | 0.74 |
| ▸ | GAA | P10253 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.74 |
| ▸ | GLA | P06280 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | HTT | P42858 | 1/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.74 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.65 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.65 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.65 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.65 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.65 |
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.61 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8191786 | 1.00 | CCR3 (0.96) | CCR3ALDH1A1ATMGAAKDM4E | |
| SCHEMBL2004615 | 0.98 | CCR3 (1.00) | CCR3ALDH1A1ATMGAAKDM4E | |
| SCHEMBL8251054 | 0.89 | CCR3 (0.81) | CCR3ALDH1A1ATMGAAKDM4E | |
| SCHEMBL3148583 | 0.89 | CCR3 (0.81) | CCR3ALDH1A1ATMGAAKDM4E | |
| SCHEMBL12642472 | 0.89 | CCR3 (0.81) | CCR3ALDH1A1ATMGAAKDM4E | |
| SCHEMBL3246849 | 0.89 | CCR3 (0.81) | CCR3ALDH1A1ATMGAAKDM4E | |
| SCHEMBL23719076 | 0.87 | CCR3 (0.80) | CCR3ALDH1A1ATMGAAKDM4E | |
| SCHEMBL8262506 | 0.87 | CCR3 (0.80) | CCR3ALDH1A1ATMGAAKDM4E | |
| SCHEMBL6218861 | 0.87 | CCR3 (0.80) | CCR3ALDH1A1ATMGAAKDM4E | |
| Hydrochloric Acid SCHEMBL7406256 | 0.87 | CCR3 (0.79) | CCR3ALDH1A1ATMGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288224-B1 | Preparation of n-arylmethyl aziridine derivatives, 1,4,7,10-tetraazacyclododecane derivatives obtained therefrom and n-arylethyl-ethanolamine sulphonate esters as intermediates | NYCOMED SALUTAR, INC. | 2001-09-11 | — | — | US | disclosed |
| US-6048979-A | CYCLOTETRAMERIZING, CLEAVAGE OF ARYLMETHYL GROUPS TO PREPARE CYCLEN AND DERIVATIVES | NYCOMED SALUTAR, INC. (US) | 2000-04-11 | — | — | US | disclosed |