Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977187 | 0.91 | PDE4A (0.61) | PDE4AKCNH2 | |
| SCHEMBL7382835 | 0.90 | PDE4A (0.48) | PDE4AKCNH2 | |
| SCHEMBL7976931 | 0.83 | PDE4A (0.60) | PDE4AKCNH2 | |
| SCHEMBL7988711 | 0.81 | PDE4A (0.67) | PDE4AKCNH2 | |
| SCHEMBL7383186 | 0.81 | PDE4A (0.53) | PDE4AKCNH2 | |
| SCHEMBL7987426 | 0.79 | PDE4A (0.65) | PDE4AKCNH2 | |
| SCHEMBL7987276 | 0.79 | PDE4A (0.56) | PDE4AKCNH2 | |
| SCHEMBL7987795 | 0.78 | PDE4A (0.62) | PDE4AKCNH2 | |
| SCHEMBL7462478 | 0.78 | PDE4A (0.64) | PDE4AKCNH2 | |
| SCHEMBL7989101 | 0.78 | PDE4A (0.65) | PDE4AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180650-B1 | ANTIINFLAMMATORY AGENTS; RESPIRATORY SYSTEM DISORDERS; SKIN DISORDERS; ANTITUMOR AGENTS | MERCK FROSST CANADA & CO. (CA) | 2001-01-30 | — | — | US | claimed |
| US-6180650-B1 | ANTIINFLAMMATORY AGENTS; RESPIRATORY SYSTEM DISORDERS; SKIN DISORDERS; ANTITUMOR AGENTS | MERCK FROSST CANADA & CO. (CA) | 2001-01-30 | — | — | US | disclosed |