Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 7/20 | 0.58 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.58 |
| ▸ | TNF | P01375 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | AGER | Q15109 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995824 | 0.77 | SMN1; SMN2 (0.50) | CYP11B1CYP11B2TNFLMNAHTT | |
| SCHEMBL124313 | 0.77 | CYP11B1 (0.67) | CYP11B1CYP11B2TNFLMNAHTT | |
| SCHEMBL7994228 | 0.75 | SMN1; SMN2 (0.48) | CYP11B1CYP11B2TNFLMNAHTT | |
| SCHEMBL4142913 | 0.75 | CYP11B1 (0.77) | CYP11B1CYP11B2TNFLMNAHTT | |
| SCHEMBL30826274 | 0.75 | CYP11B1 (0.77) | CYP11B1CYP11B2TNFLMNAHTT | |
| SCHEMBL8001714 | 0.74 | CYP11B1 (0.62) | CYP11B1CYP11B2TNFLMNAHTT | |
| SCHEMBL7983861 | 0.74 | NPSR1 (0.51) | CYP11B1CYP11B2TNFLMNAHTT | |
| Bromide SCHEMBL31253900 | 0.73 | CYP11B1 (0.75) | CYP11B1CYP11B2TNFLMNAHTT | |
| Hydrochloric Acid SCHEMBL31253891 | 0.73 | CYP11B1 (0.75) | CYP11B1CYP11B2TNFLMNAHTT | |
| SCHEMBL8001816 | 0.73 | SMN1; SMN2 (0.46) | CYP11B1CYP11B2TNFLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |