SCHEMBL7977552

SCHEMBL7977552

CN(C)S(=O)(=O)Nc1cccc(C(O)CNCCOc2ccc3c4c([nH]c3c2)CCCC4)c1

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADRB3 P13945 20/20 0.56
ADRA1A P35348 11/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7983718 0.92 ADRB3 (0.65) ADRB3ADRA1A
SCHEMBL7553370 0.92 ADRB3 (0.65) ADRB3ADRA1A
SCHEMBL7977262 0.92 ADRB3 (0.65) ADRB3ADRA1A
Hydrochloric Acid SCHEMBL7979078 0.91 ADRB3 (0.64) ADRB3ADRA1A
Hydrochloric Acid SCHEMBL7977538 0.91 ADRB3 (0.64) ADRB3ADRA1A
Hydrochloric Acid SCHEMBL7967565 0.91 ADRB3 (0.64) ADRB3ADRA1A
SCHEMBL7984103 0.87 ADRB3 (0.46) ADRB3ADRA1A
SCHEMBL7977274 0.87 ADRB3 (0.46) ADRB3ADRA1A
SCHEMBL7977272 0.87 ADRB3 (0.46) ADRB3ADRA1A
SCHEMBL6914346 0.86 ADRB3 (0.59) ADRB3ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6172099-B1 CARBAZOLE, DIBENZOFURAN, OR DIBENZOTHIOPHENE DERIVATIVES; DIETETICS, ANTIDIABETIC AGENTS; ANTILIPEMICS ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2001-01-09 US claimed
EP-0997458-A1 NOVEL TRICYCLIC COMPOUNDS HAVING SATURATED RINGS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-05-03 EP claimed
EP-0997458-A1 NOVEL TRICYCLIC COMPOUNDS HAVING SATURATED RINGS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-05-03 EP disclosed