Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28283758 | 0.80 | KDM4E (0.50) | KDM4EKMT2ATDP1ALOX15TSHR | |
| SCHEMBL14957462 | 0.78 | NAPRT (0.48) | KDM4EKMT2ATDP1ALOX15TSHR | |
| SCHEMBL27610096 | 0.77 | KDM4E (0.52) | KDM4EKMT2ATDP1ALOX15TSHR | |
| SCHEMBL13455221 | 0.77 | KDM4E (0.47) | KDM4EKMT2ATDP1ALOX15TSHR | |
| SCHEMBL27680751 | 0.77 | KDM4E (0.46) | KDM4EKMT2ATDP1ALOX15TSHR | |
| SCHEMBL12462531 | 0.76 | LCK (0.46) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31354558 | 0.76 | LCK (0.46) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8834235 | 0.76 | KDM4E (0.50) | KDM4EKMT2ATDP1ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL12488901 | 0.75 | KDM4E (0.46) | KDM4EKMT2ATDP1ALOX15TSHR | |
| SCHEMBL14919050 | 0.74 | KDM4E (0.58) | KDM4EKMT2ATDP1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114650993-B | PD-1/PD-L1 inhibitor and preparation method and application thereof | 上海华汇拓医药科技有限公司 | 2024-11-26 | — | — | CN | disclosed |
| WO-2001030782-A2 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-05-03 | — | — | WO | disclosed |