Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978671 | 1.00 | EPHX1 (0.40) | EPHX1HSD17B10HPGDSMN1; SMN2NPC1 | |
| SCHEMBL6158638 | 1.00 | EPHX1 (0.40) | EPHX1HSD17B10HPGDSMN1; SMN2NPC1 | |
| SCHEMBL7993095 | 0.96 | HSD17B10 (0.43) | EPHX1HSD17B10HPGDSMN1; SMN2NPC1 | |
| SCHEMBL19965342 | 0.96 | HSD17B10 (0.43) | EPHX1HSD17B10HPGDSMN1; SMN2NPC1 | |
| SCHEMBL16551786 | 0.96 | HSD17B10 (0.43) | EPHX1HSD17B10HPGDSMN1; SMN2NPC1 | |
| SCHEMBL7993092 | 0.96 | HSD17B10 (0.43) | EPHX1HSD17B10HPGDSMN1; SMN2NPC1 | |
| SCHEMBL29039394 | 0.96 | HSD17B10 (0.43) | EPHX1HSD17B10HPGDSMN1; SMN2NPC1 | |
| SCHEMBL6159240 | 0.96 | HSD17B10 (0.43) | EPHX1HSD17B10HPGDSMN1; SMN2NPC1 | |
| SCHEMBL5940033 | 0.86 | HSD17B10 (0.44) | EPHX1HSD17B10HPGDSMN1; SMN2NPC1 | |
| SCHEMBL5940026 | 0.86 | HSD17B10 (0.44) | EPHX1HSD17B10HPGDSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6228872-B1 | PEPTIDE-PROLYL ISOMERASE AND ROTAMASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2001-05-08 | — | — | US | disclosed |