Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GPR183 | P32249 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1694203 | 0.92 | PI4KB (0.46) | PI4KBPOLBMAPTHPGDLMNA | |
| SCHEMBL652287 | 0.90 | PI4KB (0.66) | PI4KBPOLBMAPTHPGDRAB9A | |
| SCHEMBL655473 | 0.82 | PI4KB (0.55) | PI4KBPOLBMAPTHPGDLMNA | |
| SCHEMBL654259 | 0.79 | PI4KB (0.62) | PI4KBPOLBMAPTHPGDRAB9A | |
| SCHEMBL655488 | 0.78 | PI4KB (0.62) | PI4KBPOLBMAPTHPGDRAB9A | |
| SCHEMBL1720077 | 0.77 | PI4KB (0.57) | PI4KBPOLBMAPTHPGDRAB9A | |
| SCHEMBL654772 | 0.77 | PI4KB (0.64) | PI4KBPOLBMAPTHPGDRAB9A | |
| SCHEMBL654617 | 0.77 | PI4KB (0.66) | PI4KBPOLBMAPTHPGDRAB9A | |
| SCHEMBL654583 | 0.77 | PI4KB (0.66) | PI4KBPOLBMAPTHPGDRAB9A | |
| SCHEMBL656634 | 0.76 | PI4KB (0.70) | PI4KBPOLBMAPTHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616077-A1 | ANTI-CANCER ACTIVITY OF NOVEL BICYCLIC HETEROCYCLES | Katholieke Universiteit Leuven, K.U. Leuven R&D (BE) | 2013-07-24 | — | — | EP | claimed |
| WO-2012035423-A1 | ANTI-CANCER ACTIVITY OF NOVEL BICYCLIC HETEROCYCLES | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) | 2012-03-22 | — | — | WO | claimed |