Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 5/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979266 | 1.00 | MAPT (0.41) | MAPTALDH1A1L3MBTL1TP53KCNN4 | |
| SCHEMBL7684351 | 0.94 | MAPT (0.42) | MAPTALDH1A1L3MBTL1TP53KCNN4 | |
| SCHEMBL7684346 | 0.94 | MAPT (0.42) | MAPTALDH1A1L3MBTL1TP53KCNN4 | |
| SCHEMBL7684170 | 0.93 | MAPT (0.42) | MAPTALDH1A1L3MBTL1KCNN4CA9 | |
| SCHEMBL7684171 | 0.93 | MAPT (0.42) | MAPTALDH1A1L3MBTL1KCNN4CA9 | |
| SCHEMBL7688767 | 0.92 | KCNN4 (0.41) | MAPTALDH1A1L3MBTL1TP53KCNN4 | |
| SCHEMBL7688768 | 0.92 | KCNN4 (0.41) | MAPTALDH1A1L3MBTL1TP53KCNN4 | |
| SCHEMBL7680079 | 0.92 | MAPT (0.36) | MAPTALDH1A1L3MBTL1CA9MEN1 | |
| SCHEMBL7680078 | 0.92 | MAPT (0.36) | MAPTALDH1A1L3MBTL1CA9MEN1 | |
| SCHEMBL7682226 | 0.90 | MAPT (0.43) | MAPTALDH1A1L3MBTL1TP53KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303783-B1 | 1- (3-Heterocyclylphenyl) isothiourea, -isourea, -guanidine and -amidine herbicidal agents | AMERICAN CYANAMID CO. | 2001-10-16 | — | — | US | disclosed |
| EP-0985670-A1 | 1-(3-Heterocyclylphenyl)isothiourea, -isourea, -guanidine and -amidine compounds as herbicides | American Cyanamid Company (US) | 2000-03-15 | — | — | EP | disclosed |