Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 19/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 11/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7551566 | 1.00 | ADRB3 (0.50) | ADRB3ADRA1ADRD2DRD3 | |
| SCHEMBL7979270 | 1.00 | ADRB3 (0.50) | ADRB3ADRA1ADRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7979111 | 0.99 | ADRB3 (0.49) | ADRB3ADRA1ADRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7967312 | 0.99 | ADRB3 (0.49) | ADRB3ADRA1ADRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7977244 | 0.99 | ADRB3 (0.49) | ADRB3ADRA1ADRD2DRD3 | |
| SCHEMBL7967003 | 0.93 | ADRB3 (0.48) | ADRB3ADRA1ADRD2DRD3 | |
| SCHEMBL7967006 | 0.93 | ADRB3 (0.48) | ADRB3ADRA1ADRD2DRD3 | |
| SCHEMBL7980458 | 0.92 | ADRB3 (0.43) | ADRB3ADRA1A | |
| SCHEMBL7979102 | 0.91 | ADRB3 (0.54) | ADRB3ADRA1A | |
| SCHEMBL7980670 | 0.91 | ADRB3 (0.50) | ADRB3ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997458-A1 | NOVEL TRICYCLIC COMPOUNDS HAVING SATURATED RINGS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-05-03 | — | — | EP | claimed |
| US-6172099-B1 | CARBAZOLE, DIBENZOFURAN, OR DIBENZOTHIOPHENE DERIVATIVES; DIETETICS, ANTIDIABETIC AGENTS; ANTILIPEMICS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0997458-A1 | NOVEL TRICYCLIC COMPOUNDS HAVING SATURATED RINGS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-05-03 | — | — | EP | disclosed |