Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 15/20 | 0.58 |
| ▸ | HRH1 | P35367 | 15/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7244762 | 1.00 | HRH2 (0.58) | HRH2HRH1EPHX2HRH3 | |
| SCHEMBL7978302 | 0.87 | HRH2 (0.61) | HRH2HRH1HRH3 | |
| SCHEMBL7245178 | 0.87 | HRH2 (0.61) | HRH2HRH1HRH3 | |
| SCHEMBL7243588 | 0.87 | HRH2 (0.61) | HRH2HRH1HRH3 | |
| SCHEMBL7244782 | 0.86 | HRH2 (0.65) | HRH2HRH1HRH3 | |
| SCHEMBL7250883 | 0.86 | HRH2 (0.65) | HRH2HRH1HRH3 | |
| SCHEMBL7251111 | 0.85 | HRH2 (0.62) | HRH2HRH1HRH3 | |
| SCHEMBL7246489 | 0.82 | HRH2 (0.68) | HRH2HRH1HRH3 | |
| SCHEMBL7251299 | 0.82 | HRH2 (0.80) | HRH2HRH1HRH3 | |
| SCHEMBL7250960 | 0.82 | HRH2 (0.68) | HRH2HRH1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001066534-A2 | CYCLIC AND BICYCLIC DIAMINO HISTAMINE-3 RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2001-09-13 | — | — | WO | disclosed |