Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24575950 | 0.84 | HPGD (0.72) | SMN1; SMN2USP2HPGDTP53ALOX12 | |
| SCHEMBL4420466 | 0.82 | SMN1; SMN2 (0.66) | SMN1; SMN2USP2HPGDTP53ALOX12 | |
| SCHEMBL6061649 | 0.82 | SMN1; SMN2 (0.66) | SMN1; SMN2USP2HPGDTP53ALOX12 | |
| SCHEMBL4429350 | 0.82 | SMN1; SMN2 (0.66) | SMN1; SMN2USP2HPGDTP53ALOX12 | |
| SCHEMBL2864022 | 0.82 | SMN1; SMN2 (0.66) | SMN1; SMN2USP2HPGDTP53ALOX12 | |
| SCHEMBL25955957 | 0.81 | HPGD (0.60) | SMN1; SMN2USP2HPGDTP53ALOX12 | |
| SCHEMBL31349310 | 0.81 | HPGD (0.60) | SMN1; SMN2USP2HPGDTP53ALOX12 | |
| SCHEMBL4812101 | 0.81 | SMN1; SMN2 (0.64) | SMN1; SMN2USP2HPGDTP53ALOX12 | |
| SCHEMBL6293470 | 0.81 | SMN1; SMN2 (0.64) | SMN1; SMN2USP2HPGDTP53ALOX12 | |
| SCHEMBL1101625 | 0.81 | SMN1; SMN2 (0.64) | SMN1; SMN2USP2HPGDTP53ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |