Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 10/20 | 0.48 |
| ▸ | F10 | P00742 | 9/20 | 0.48 |
| ▸ | PLG | P00747 | 7/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ITK | Q08881 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.34 |
| ▸ | MARK3 | P27448 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979857 | 0.84 | F2 (0.45) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7425127 | 0.82 | F2 (0.48) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7984674 | 0.80 | F2 (0.65) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7979862 | 0.80 | F2 (0.65) | F2F10PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7422765 | 0.80 | F2 (0.64) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7968917 | 0.79 | F2 (0.48) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7985234 | 0.78 | F2 (0.69) | F2F10PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7981002 | 0.77 | F2 (0.53) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL7426925 | 0.74 | F2 (0.72) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL8029667 | 0.73 | ITK (0.43) | F2F10PLGPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |