Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.85 |
| ▸ | F10 | P00742 | 2/20 | 0.85 |
| ▸ | PRMT1 | Q99873 | 5/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.49 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.49 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5032861 | 1.00 | F2 (0.85) | F2F10PRMT1ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL5031493 | 0.98 | F2 (0.82) | F2F10PRMT1ITGB3ITGA2B | |
| SCHEMBL5030493 | 0.98 | F2 (0.88) | F2F10PRMT1ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL5034833 | 0.97 | F2 (0.85) | F2F10PRMT1ITGB3ITGA2B | |
| SCHEMBL5028071 | 0.95 | F2 (0.88) | F2F10PRMT1ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL5034703 | 0.94 | F2 (0.85) | F2F10PRMT1ITGB3ITGA2B | |
| SCHEMBL7978262 | 0.93 | F2 (0.74) | F2F10PRMT1ITGB3ITGA2B | |
| SCHEMBL237460 | 0.92 | F2 (1.00) | F2F10PRMT1TPSAB1TPSD1 | |
| Hydrochloric Acid SCHEMBL5028046 | 0.90 | F2 (0.97) | F2F10PRMT1TPSAB1TPSD1 | |
| SCHEMBL5031398 | 0.88 | F2 (0.65) | F2F10PRMT1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001072742-A1 | BISAMIDINO COMPOUNDS AS NHE-3 INHIBITORS | MERCK PATENT GMBH (US) | 2001-10-04 | — | — | WO | claimed |
| WO-2001072742-A1 | BISAMIDINO COMPOUNDS AS NHE-3 INHIBITORS | MERCK PATENT GMBH (US) | 2001-10-04 | — | — | WO | disclosed |