Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.73 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | KDM1A | O60341 | 7/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | TLR2 | O60603 | 5/20 | 0.55 |
| ▸ | TLR1 | Q15399 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154005 | 1.00 | SMN1; SMN2 (0.73) | SMN1; SMN2NPSR1CNR1KDM1AEPHX2 | |
| SCHEMBL6153775 | 1.00 | SMN1; SMN2 (0.73) | SMN1; SMN2NPSR1CNR1KDM1AEPHX2 | |
| SCHEMBL3457343 | 1.00 | SMN1; SMN2 (0.73) | SMN1; SMN2NPSR1CNR1KDM1AEPHX2 | |
| SCHEMBL2362144 | 0.89 | SMN1; SMN2 (0.60) | SMN1; SMN2NPSR1CNR1KDM1AEPHX2 | |
| SCHEMBL2362145 | 0.89 | SMN1; SMN2 (0.60) | SMN1; SMN2NPSR1CNR1KDM1AEPHX2 | |
| SCHEMBL2776191 | 0.85 | SMN1; SMN2 (0.55) | SMN1; SMN2NPSR1CNR1KDM1AEPHX2 | |
| SCHEMBL2776196 | 0.85 | SMN1; SMN2 (0.55) | SMN1; SMN2NPSR1CNR1KDM1AEPHX2 | |
| SCHEMBL25021708 | 0.85 | SMN1; SMN2 (1.00) | SMN1; SMN2NPSR1CNR1KDM1AEPHX2 | |
| SCHEMBL14544486 | 0.85 | SMN1; SMN2 (1.00) | SMN1; SMN2NPSR1CNR1KDM1AEPHX2 | |
| SCHEMBL13794162 | 0.85 | SMN1; SMN2 (1.00) | SMN1; SMN2NPSR1CNR1KDM1AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |