Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | IDE | P14735 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7576799 | 0.84 | HPRT1 (0.51) | HPRT1MEN1KMT2ALMNA | |
| SCHEMBL7570074 | 0.82 | HPRT1 (0.53) | HPRT1KMT2ALMNA | |
| SCHEMBL7575108 | 0.82 | HPRT1 (0.53) | HPRT1 | |
| SCHEMBL7570913 | 0.81 | HPRT1 (0.50) | HPRT1 | |
| SCHEMBL7570961 | 0.80 | HPRT1 (0.46) | TSHRHPRT1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7568062 | 0.80 | HPRT1 (0.48) | HPRT1NPSR1MEN1KMT2ALMNA | |
| SCHEMBL7982326 | 0.80 | HPRT1 (0.51) | HPRT1TDP1 | |
| SCHEMBL7575074 | 0.79 | HPRT1 (0.48) | TSHRHPRT1POLBMEN1KMT2A | |
| SCHEMBL7568116 | 0.79 | HPRT1 (0.46) | HPRT1 | |
| SCHEMBL7571914 | 0.79 | HPRT1 (0.49) | TSHRHPRT1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297226-B1 | TREATING A DISEASE OR A CONDITION IN A MAMMAL TREATABLE BY INHIBITING THE ACTIVITY OF A MONOAMINE OXIDASE | NEOTHERAPEUTICS, INC. | 2001-10-02 | — | — | US | claimed |
| US-6297226-B1 | TREATING A DISEASE OR A CONDITION IN A MAMMAL TREATABLE BY INHIBITING THE ACTIVITY OF A MONOAMINE OXIDASE | NEOTHERAPEUTICS, INC. | 2001-10-02 | — | — | US | disclosed |