Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 19/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980830 | 0.93 | ADRB3 (0.49) | ADRB3ADRB1 | |
| SCHEMBL7600305 | 0.89 | ADRB3 (0.54) | ADRB3ADRB2 | |
| SCHEMBL7979102 | 0.89 | ADRB3 (0.54) | ADRB3ADRB2 | |
| SCHEMBL7600308 | 0.89 | ADRB3 (0.54) | ADRB3ADRB2 | |
| Hydrochloric Acid SCHEMBL7983471 | 0.88 | ADRB3 (0.54) | ADRB3ADRB2 | |
| Hydrochloric Acid SCHEMBL7979217 | 0.88 | ADRB3 (0.54) | ADRB3ADRB2 | |
| SCHEMBL7967379 | 0.88 | ADRB3 (0.54) | ADRB3 | |
| SCHEMBL7967135 | 0.88 | ADRB3 (0.54) | ADRB3 | |
| Hydrochloric Acid SCHEMBL7979220 | 0.88 | ADRB3 (0.54) | ADRB3ADRB2 | |
| SCHEMBL7977531 | 0.88 | ADRB3 (0.54) | ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172099-B1 | CARBAZOLE, DIBENZOFURAN, OR DIBENZOTHIOPHENE DERIVATIVES; DIETETICS, ANTIDIABETIC AGENTS; ANTILIPEMICS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0997458-A1 | NOVEL TRICYCLIC COMPOUNDS HAVING SATURATED RINGS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-05-03 | — | — | EP | disclosed |