Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 10/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 5/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980814 | 1.00 | ADRB3 (0.46) | ADRB3MAPTLMNATP53ADRB2 | |
| Hydrochloric Acid SCHEMBL7980619 | 0.99 | ADRB3 (0.45) | ADRB3MAPTLMNATP53ADRB2 | |
| Hydrochloric Acid SCHEMBL7980621 | 0.99 | ADRB3 (0.45) | ADRB3MAPTLMNATP53ADRB2 | |
| SCHEMBL7984103 | 0.93 | ADRB3 (0.46) | ADRB3ADRB2CHRM3 | |
| SCHEMBL7977274 | 0.93 | ADRB3 (0.46) | ADRB3ADRB2CHRM3 | |
| SCHEMBL7977272 | 0.93 | ADRB3 (0.46) | ADRB3ADRB2CHRM3 | |
| SCHEMBL7967234 | 0.93 | ADRB3 (0.44) | ADRB3MAPTLMNATP53ADRB2 | |
| SCHEMBL7967272 | 0.93 | ADRB3 (0.44) | ADRB3MAPTLMNATP53ADRB2 | |
| Hydrochloric Acid SCHEMBL7983499 | 0.92 | ADRB3 (0.46) | ADRB3ADRB2CHRM3 | |
| Hydrochloric Acid SCHEMBL7633596 | 0.92 | ADRB3 (0.46) | ADRB3ADRB2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172099-B1 | CARBAZOLE, DIBENZOFURAN, OR DIBENZOTHIOPHENE DERIVATIVES; DIETETICS, ANTIDIABETIC AGENTS; ANTILIPEMICS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0997458-A1 | NOVEL TRICYCLIC COMPOUNDS HAVING SATURATED RINGS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-05-03 | — | — | EP | disclosed |