Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 18/20 | 0.77 |
| ▸ | LYN | P07948 | 2/20 | 0.55 |
| ▸ | BTK | Q06187 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7969628 | 0.90 | LCK (0.77) | LCKLYNBTK | |
| SCHEMBL7981144 | 0.88 | LCK (0.74) | LCKLYNBTK | |
| SCHEMBL7970143 | 0.88 | LCK (0.77) | LCKLYNBTK | |
| SCHEMBL7979866 | 0.87 | LCK (1.00) | LCK | |
| SCHEMBL7982170 | 0.85 | LCK (0.79) | LCK | |
| SCHEMBL7983951 | 0.85 | LCK (0.73) | LCKLYNBTK | |
| SCHEMBL7969592 | 0.79 | LCK (0.83) | LCK | |
| SCHEMBL7983457 | 0.79 | LCK (0.74) | LCK | |
| SCHEMBL7970071 | 0.79 | LCK (0.72) | LCKLYNBTK | |
| SCHEMBL7969998 | 0.79 | LCK (0.69) | LCKLYNBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | claimed |
| WO-1999009845-A1 | IMIDAZOQUINOXALINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-04 | — | — | WO | claimed |
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | disclosed |