Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 7/20 | 0.53 |
| ▸ | BRD4 | O60885 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31402329 | 0.79 | CREBBP (0.60) | CREBBPBRD4PARP1 | |
| SCHEMBL5672928 | 0.79 | CREBBP (0.60) | CREBBPBRD4PARP1 | |
| SCHEMBL7985936 | 0.72 | PARP1 (0.38) | CREBBPBRD4ALDH1A1PARP1PGR | |
| SCHEMBL16300073 | 0.71 | CREBBP (0.50) | CREBBPBRD4ALDH1A1PARP1ALOX12 | |
| SCHEMBL17680581 | 0.69 | CREBBP (1.00) | CREBBPBRD4 | |
| SCHEMBL17680970 | 0.69 | CREBBP (0.68) | CREBBPBRD4 | |
| SCHEMBL10558622 | 0.69 | CREBBP (0.47) | CREBBPBRD4ALDH1A1 | |
| SCHEMBL14416706 | 0.67 | BRD4 (0.39) | CREBBPBRD4ALDH1A1 | |
| SCHEMBL31402309 | 0.67 | CREBBP (0.58) | CREBBPBRD4 | |
| SCHEMBL4971260 | 0.66 | BRD4 (0.52) | CREBBPBRD4ALDH1A1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191127-B1 | ANTIINFLAMMATORY AGENTS, AUTOIMMUNE DISEASES, CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |