Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 6/20 | 0.84 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1779582 | 0.92 | CHRM2 (0.68) | CHRM2KDM4ESCN8APOLBMEN1 | |
| Hydrochloric Acid SCHEMBL27669851 | 0.90 | CHRM2 (0.66) | CHRM2KDM4ESCN8APOLBMEN1 | |
| SCHEMBL536987 | 0.88 | CHRM2 (0.74) | CHRM2SLC2A1KDM4ESCN8APOLB | |
| SCHEMBL22839742 | 0.88 | CHRM2 (0.92) | CHRM2SLC2A1KDM4ESCN8AMEN1 | |
| Hydrochloric Acid SCHEMBL29079569 | 0.87 | CHRM2 (0.72) | CHRM2SLC2A1KDM4ESCN8APOLB | |
| SCHEMBL2930997 | 0.84 | CHRM2 (0.85) | CHRM2SLC2A1KDM4ESCN8AMEN1 | |
| SCHEMBL20870837 | 0.83 | CHRM2 (0.83) | CHRM2SLC2A1KDM4ESCN8AGAA | |
| SCHEMBL29335922 | 0.83 | CHRM2 (0.83) | CHRM2SLC2A1KDM4ESCN8AGAA | |
| SCHEMBL20850579 | 0.83 | CHRM2 (0.83) | CHRM2SLC2A1KDM4ESCN8AGAA | |
| SCHEMBL4919379 | 0.82 | CHRM2 (0.81) | CHRM2KDM4ESCN8AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214833-B1 | MADE BY ACYLATION | ZAMBON GROUP S.P.A. (IT) | 2001-04-10 | — | — | US | disclosed |
| EP-0797579-B1 | ERYTHROMYCIN A 9-0-OXIME DERIVATIVES ENDOWED WITH ANTIBIOTIC ACTIVITY | ZAMBON SPA (IT) | 2000-03-15 | — | — | EP | disclosed |
| EP-0970075-A1 | PYRIMIDINONE-1,3-OXATHIOLANE DERIVATIVES WITH ANTIVIRAL ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998043972-A1 | PYRIMIDINONE-1,3-OXATHIOLANE DERIVATIVES WITH ANTIVIRAL ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 1998-10-08 | — | — | WO | disclosed |