SCHEMBL7981930

SCHEMBL7981930

NCCOc1c(Cl)cc(OCC=C(Br)Br)cc1Cl

nearest known ligand 0.49

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PLAU P00749 4/20 0.49
TTR P02766 1/20 0.33
TAAR1 Q96RJ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7978120 0.93 PLAU (0.41) PLAUTTR
SCHEMBL7981958 0.91 PLAU (0.40) PLAU
SCHEMBL7981941 0.90 PLAU (0.40) PLAU
SCHEMBL7975926 0.90 PLAU (0.39) PLAU
SCHEMBL8661481 0.87 PLAU (0.31) PLAU
SCHEMBL8407424 0.86 PLAU (0.33) PLAU
SCHEMBL7977389 0.86 PLAU (0.50) PLAUTTRTAAR1
SCHEMBL7979627 0.86 KLK1 (0.37) PLAUTAAR1
SCHEMBL8409038 0.85 PLAU (0.33) PLAU
Hydrochloric Acid SCHEMBL31538885 0.85 PLAU (0.49) PLAUTTRTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6214835-B1 CONTROLLING INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-04-10 US disclosed
EP-0824514-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2000-09-06 EP disclosed
US-6028100-A Dihalopropene compounds, insecticides containing them as active ingredients, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-02-22 US disclosed
US-5952386-A EXCELLENT INSECTICIDAL ACTIVITY FOR THE CONTROL OF NOXIOUS INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-09-14 US disclosed
WO-1996033160-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-10-24 WO disclosed