Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970113 | 0.93 | LCK (0.87) | LCKKMT2A | |
| SCHEMBL7980767 | 0.83 | LCK (1.00) | LCK | |
| SCHEMBL7982128 | 0.81 | LCK (1.00) | LCK | |
| SCHEMBL7984724 | 0.81 | LCK (1.00) | LCK | |
| SCHEMBL7980884 | 0.81 | LCK (1.00) | LCK | |
| SCHEMBL7984163 | 0.81 | LCK (0.67) | LCK | |
| SCHEMBL7983559 | 0.80 | LCK (0.71) | LCK | |
| SCHEMBL7970006 | 0.80 | LCK (0.78) | LCK | |
| SCHEMBL7969728 | 0.80 | LCK (0.69) | LCK | |
| SCHEMBL7969485 | 0.79 | LCK (1.00) | LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | claimed |
| WO-1999009845-A1 | IMIDAZOQUINOXALINE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-04 | — | — | WO | claimed |
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | disclosed |