Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 9/20 | 0.49 |
| ▸ | ESR1 | P03372 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11114155 | 0.92 | ESR2 (0.47) | ESR2ESR1HSD17B10MEN1KMT2A | |
| SCHEMBL9813136 | 0.91 | ESR2 (0.48) | ESR2ESR1HSD17B10MEN1KMT2A | |
| SCHEMBL1888816 | 0.91 | MEN1 (0.51) | ESR2ESR1HSD17B10MEN1KMT2A | |
| SCHEMBL6572282 | 0.91 | MEN1 (0.51) | ESR2ESR1HSD17B10MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9813279 | 0.90 | ESR2 (0.48) | ESR2ESR1HSD17B10MEN1KMT2A | |
| Potassium SCHEMBL10738982 | 0.90 | MEN1 (0.50) | ESR2ESR1HSD17B10MEN1KMT2A | |
| SCHEMBL10738974 | 0.90 | MEN1 (0.50) | ESR2ESR1HSD17B10MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9815629 | 0.90 | ESR2 (0.47) | ESR2ESR1HSD17B10MEN1KMT2A | |
| SCHEMBL9813159 | 0.90 | ESR2 (0.47) | ESR2ESR1HSD17B10MEN1KMT2A | |
| Potassium Ion SCHEMBL10738962 | 0.89 | ESR2 (0.48) | ESR2ESR1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001014334-A1 | FLUORENONE COMPOUNDS WITH MODIFIED 7-POSITION SUBSTITUENTS FOR TREATING AND PREVENTING BRAIN AND SPINAL INJURY | QUESTCOR PHARMACEUTICALS, INC. (US) | 2001-03-01 | — | — | WO | claimed |
| WO-2001014334-A1 | FLUORENONE COMPOUNDS WITH MODIFIED 7-POSITION SUBSTITUENTS FOR TREATING AND PREVENTING BRAIN AND SPINAL INJURY | QUESTCOR PHARMACEUTICALS, INC. (US) | 2001-03-01 | — | — | WO | disclosed |